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Metformin onset of action: "Metformin also increases your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose made by your liver. Metformin can rarely cause a serious condition called lactic acidosis. Overall, Metformin reduces blood sugar levels can rise too high. Metformin belongs to the class of drugs known as biguanides. Glucophage tablets contain the active ingredient Metformin hydrochloride. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. Glucophage is from the biguanide class of oral anti-hyperglycemic agents. Metformin is used as a first line treatment of type 2 diabetes. Metformin decreases the amount of glucose in the blood."