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Deltasone use is likely to change liver enzyme blood testing and interfere with testing for thyroid diseases. Prednisolone is commonly used for several days before the needed effect is achieved. Corticosteroids, including prednisone, are commonly used to suppress the immune system. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Since prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Before the needed effect is achieved. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Corticosteroid which is often simply called steroid, but it may still pose a risk to the infant.